Longevity
MOTS-C
Mitochondrial-Derived Peptide
Mechanism
Sixteen-amino-acid peptide encoded within the 12S rRNA region of mitochondrial DNA — one of the first mitokines identified. Activates AMPK following one-carbon metabolic stress, affecting downstream mTOR and gluconeogenic pathways. In vivo rodent studies show improved insulin sensitivity and metabolic flexibility.
Scientific Profile
Supplied to verified B2B accounts only — research institutions under RUO, or licensed 503A compounding pharmacies as API. Not FDA-approved for human or veterinary therapeutic use. See the disclaimer.